1258327-08-0

  • Product Name:(11aS)-12-Hydroxy-1,10-di(naphthalen-1-yl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide
  • Molecular Formula:C37H27O4P
  • Purity:99%
  • Molecular Weight:566.593
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Product Details

pd_meltingpoint:>300℃

Purity:99%

Sale Buy Reliable Quality (11aS)-12-Hydroxy-1,10-di(naphthalen-1-yl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide 1258327-08-0 Efficient Shipping

  • Molecular Formula:C37H27O4P
  • Molecular Weight:566.593
  • Melting Point:>300℃ 
  • PSA:65.57000 
  • Density:1.44 
  • LogP:9.37710 

1258327-08-0 Relevant articles

SPINOL-derived phosphoric acids: Synthesis and application in enantioselective Friedel-Crafts reaction of indoles with imines

Xu, Fangxi,Huang, Dan,Han, Chao,Shen, Wei,Lin, Xufeng,Wang, Yanguang

, p. 8677 - 8680 (2010)

A new class of chiral phosphoric acids w...

1258327-08-0 Process route

(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol
1292849-40-1

(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol

(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate
1258327-08-0,1297613-73-0

(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate

Conditions
Conditions Yield
(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol; With pyridine; trichlorophosphate; at 0 - 70 ℃; for 3h; Inert atmosphere;
With water; at 0 - 110 ℃; for 4h; Inert atmosphere;
(S)-7,7'-bis(1-methoxymethoxy)-1,1'-spirobiindane

(S)-7,7'-bis(1-methoxymethoxy)-1,1'-spirobiindane

(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate
1258327-08-0,1297613-73-0

(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / diethyl ether; hexane / 6 h / -78 - 20 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / methanol; chloroform; water / 3 h / Inert atmosphere; Reflux
3.1: 5% Pd(II)/C(eggshell); potassium carbonate / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere
4.1: pyridine; trichlorophosphate / 3 h / 0 - 70 °C / Inert atmosphere
4.2: 4 h / 0 - 110 °C / Inert atmosphere
With pyridine; hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; 5% Pd(II)/C(eggshell); potassium carbonate; trichlorophosphate; In 1,4-dioxane; methanol; diethyl ether; hexane; chloroform; water; 3.1: Suzuki coupling;

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